Head: Prof. Dr. med. Stefan Leucht

Link to own homepage : https://ebmpp.org/en

Work areas

• Evidence-based medicine in psychiatry and psychotherapy
• Systematic reviews and meta-analyses
• Cochrane reviews
• Network meta-analyses
• Diagnostic test reviews
• Individual patient data meta-analyses
• Dose- Aspects of clinical trials
• Participatory decision making
• Therapy apps
• Surveys

Current projects

• Evidence on antipsychotic drug treatment for schizophrenia from Western and Chinese trials: building a comprehensive database, training investigators and applying network meta-analysis (DFG)
• Treatment of acute agitation and aggression under real-life conditions. Data from individual patients, network meta-analysis of randomized controlled trials (BMBF)
• Muscarinic agonists and positive allosteric modulators in animal models of schizophrenia:a systematic review and meta-analysis (ANIMUS, BMBF)
• Antipsychotics and their effects on cognitive function: A systematic review, pairwise meta-analysis and network meta-analysis (BMBF)
• Individual-patient data meta-analysis on the efficacy of clozapine compared with second-generation antipsychotics in patients with treatment-resistant schizophrenia (BMBF)
• Non-invasive brain stimulation in treatment-resistant schizophrenia: A systematic review and network meta-analysis (BMBF)
• Psychological interventions in the early phase of schizophrenia: a systematic review and network meta-analysis (BMBF)
• Sexual side effects of antipsychotics: A systematic review with single-arm,pairwise and network meta-analysis of randomized controlled trials and non-randomized studies (BMBF)
• Evaluation of a school project to destigmatize mental illness (German Center for Mental Health, BMBF)
• Living meta-analysis of pharmacokinetic drug-gene interactions in psychiatry: The importance of CYP450 genetic polymorphism (Humboldt Foundation)
• Use of an evidence-based decision aid on antipsychotics for hospitalized patients with schizophrenia (EVENT, Innovation Fund)
• IT-based relapse monitoring for schizophrenia (ILIA; Innovation Fund)
• Global Alliance for Living Evidence on aNxiety, depressiOn and pSychosis (GALENOS; Wellcome Trust)

Publications

https://pubmed.ncbi.nlm.nih.gov/?term=Leucht-S&sort=date

Cooperation partners (selection)

• Link to map: https://ebmpp.org/en/cooperations
• German Center for Mental Health
• World Health Organization
• Cochrane Schizophrenia Group
• University of Oxford
• University of Illinois at Chicago
• Kyoto University
• Hoofstra University New York
• Shanghai Mental Health Center
• University of Haifa